This site is intended for patients prescribed SIMPONI (golimumab). If you are a Healthcare Professional then go to the HCP site or if you are a member of the public, please visit our public site.


Please continue to take your medication as instructed by your doctor or pharmacist. If you are concerned that you may have symptoms of COVID-19 or you are concerned about having been in contact with someone who has symptoms of COVID-19 then self-isolate, consult NHS 111 ( and also contact your GP or referring centre (consultant or clinical nurse specialist) for further advice.

Any questions?

Here are the answers to some of the most commonly asked questions about taking SIMPONI for:

  • Rheumatoid Arthritis (RA)
  • Psoriatic Arthritis (PsA)
  • Non-Radiographic Axial Spondyloarthritis (nr-axSpA)
  • Ankylosing Spondylitis (AS)
  • Ulcerative Colitis (UC)
What should I do if I miss my dose?

If you are less than two weeks late:

  • Inject the forgotten dose as soon as you remember and keep to your current schedule.

If you are more than two weeks late:

  • Inject the forgotten dose as soon as you remember and ask your doctor or pharmacist when to take the next dose.
When will I notice a difference?

For UC Patients

Patients usually show clinical improvement within 12-14 weeks of treatment, after the first 4 doses.

For RA, PsA, nr-axSpA, AS

Most patients notice a difference after taking 3-4 doses (around 12-14 weeks after the first treatment):

  • RA and PsA patients usually notice a reduction in signs and symptoms of your disease, slowing down of the damage to your bones and improved physical function.
  • AS and nr-axSpA patients may notice a reduction in signs and symptoms of your disease and improved physical function
Will the injection hurt?

The SmartJect pen and syringe both have a very thin, short needle that injects just below the skin surface to help keep pain to a minimum. SIMPONI has been specially formulated to reduce the likelihood of feeling any pain.

Can I take SIMPONI with other medication?

SIMPONI must not be taken in combination with medicines containing anakinra or abatacept. Tell your doctor or pharmacist about any other medicines you are taking. You should also notify them if you have recently had, or are due to have, a vaccine.

What about allergies?

The SmartJect pen and pre-filled syringe contain latex – talk to your doctor before taking SIMPONI if you have a latex allergy.

SIMPONI contains sorbitol (E420). If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking SIMPONI.

What about going on holiday?

The fridge is the best place to keep SIMPONI. But for times when you need a little extra flexibility, it’s also safe to store it at room temperature (below 25°C) for a single period of up to 30 days*. That means you have the freedom to take SIMPONI along wherever life takes you. Once you take SIMPONI out of the fridge, make sure you write a new expiry date (30 days’ time) on the carton so you know how long you can keep it for.

*Do NOT return SIMPONI to the fridge if it has reached room temperature. DISCARD your SIMPONI if not used by the NEW expiry date you have written on the carton, or the original one printed on the carton – whichever is the earlier.

Patient Reminder Card

Don't forget you should always carry your Patient Reminder Card with you and show it to any healthcare professional who is treating you. You can find this in your SIMPONI box.

Patient Reminder Card

Patient Reminder Card


For further information about SIMPONI (golimumab) please contact our Medical Information Department at:

Medical Information Department

Merck Sharp & Dohme (UK) Limited

Registered Office:

120 Moorgate



United Kingdom

Tel: 01992 467272


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  12. Brophy S et al. Semin Arthritis Rheum 42:361-367

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