This site is intended for patients prescribed Simponi (golimumab). If you are a Healthcare Professional then go to the HCP site or if you are a member of the public, please visit our public site.

Any questions?

Here are the answers to some of the most commonly asked questions about taking Simponi for:

  • Rheumatoid Arthritis (RA)
  • Psoriatic Arthritis (PsA)
  • Non-Radiographic Axial Spondyloarthritis (nr-axSpA)
  • Ankylosing Spondylitis (AS)
  • Ulcerative Colitis (UC)
What should I do if I miss my dose?

If you are less than two weeks late:

  • Inject the forgotten dose as soon as you remember and keep to your current schedule.

If you are more than two weeks late:

  • Inject the forgotten dose as soon as you remember and ask your doctor or pharmacist when to take the next dose.
When will I notice a difference?

For UC Patients

Patients usually show clinical improvement within 12-14 weeks of treatment, after the first 4 doses.

For RA, PsA, nr-axSpA, AS

Most patients notice a difference after taking 3-4 doses (around 12-14 weeks after the first treatment):

  • RA and PsA patients usually notice a reduction in signs and symptoms of your disease, slowing down of the damage to your bones and improved physical function.
  • AS and nr-axSpA patients may notice a reduction in signs and symptoms of your disease and improved physical function
Will the injection hurt?

The SmartJect pen and syringe both have a very thin, short needle that injects just below the skin surface to help keep pain to a minimum. Simponi has been specially formulated to reduce the likelihood of feeling any pain.

Can I take Simponi with other medication?

Simponi must not be taken in combination with medicines containing anakinra or abatacept. Tell your doctor or pharmacist about any other medicines you are taking. You should also notify them if you have recently had, or are due to have, a vaccine.

What about allergies?

The SmartJect pen and pre-filled syringe contain latex – talk to your doctor before taking Simponi if you have a latex allergy.

Simponi contains sorbitol (E420). If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking Simponi.

What about going on holiday?

If you need to take your Simponi dose when you are on holiday, make sure it is kept at the right temperature (between 2°C and 8°C) while travelling. You can organise your delivery to fit around your holiday plans.

Patient Alert Card

Don't forget you should always carry your Patient Alert Card with you and show it to any healthcare professional who is treating you. You can find this in your Simponi box.

Patient Alert Card


For further information about Simponi (golimumab) please contact our Medical Information Department at:

Medical Information Department

Merck Sharp & Dohme Ltd.

Hertford Road



EN11 9BU

Tel: 01992 467272


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