This site is intended for patients prescribed Simponi (golimumab). If you are a Healthcare Professional then go to the HCP site or if you are a member of the public, please visit our public site.

Getting Ready

Although your healthcare professional should have taken you through how to self inject, this step-by-step guide is here for you to refer to at any time. If you have not been trained please contact your doctor, nurse or pharmacist.

When it has reached room temperature, take the SmartJect pen or syringe out of the carton.

Wash your hands with warm soapy water and dry with a clean towel.

Use an alcohol wipe to clean a 5 x 5cm area around your chosen injection site and allow the skin to air dry.

Things you should check:

  • The expiry date
  • The security seal
  • The liquid in the observation window is colourless to light yellow in colour
  • Do not use if it looks cloudy or has large particles in it

When you're ready to inject

Please choose either the SmartJect Pen or the Syringe:

SmartJect Pen

Click the play icon to view the injection video guide for the pre-filled pen.

View text instructions

Syringe

Click the play icon to view the injection video guide for the pre-filled syringe.

View text instructions

1

Twist and remove the cap and then throw it away - don't put it back on as this may damage the needle. You should inject within 5 minutes of the cap being removed.

Check expiry date:

Check the expiration date (as indicated as "EXP") on the pre-filled pen.

You can also check the expiration date printed on the carton. Do not use the pre-filled pen if the expiration date has passed. The expiration date refers to the last day of the month. Please contact your doctor or pharmacist for assistance.

2

Make sure you are sitting comfortably with your muscles relaxed. Being careful not to push the button, press the SmartJect® pen firmly against your skin.

3

When you feel ready, you can inject by simply pressing the button - when the injection starts, you should hear a loud click. You will not be able to push down the button unless the pen is held firmly against the skin.

4

You may be startled by the click, but be careful not to move the pen once the injection has started.

5

Continue holding the pen firmly against the skin until you hear a second click - otherwise you may not receive the full dose. This should happen after 3-15 seconds.

If you have difficulty hearing, wait at least 15 seconds before moving the pen away.

6

If the injection has been successful, you should be able to see a yellow indicator. If you can’t see it, contact your healthcare professional, but do not take another dose.

Don’t worry if there is a small amount of blood or liquid at the injection site afterwards – this is normal. It may help to press on the area with a cotton ball, but do not rub the skin.

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1

Hold the syringe in one hand between your thumb and fingers - you should only hold it by the main body of the syringe

Check expiry date:

Check the expiration date (as indicated by "EXP") on the label by looking through the viewing window located within the body of the pre-filled syringe.

If you cannot see the expiration date through the viewing window, hold the pre-filled syringe by its body and rotate the needle cover to line up the expiration date to the viewing window.

You can also check the expiration date printed on the carton. Do not use the pre-filled syringe if the expiration date has passed. The expiration date refers to the last day of the month. Please contact your doctor or pharmacist for assistance.

2

Pull the needle cover off and throw it away - don't put it back on as this may damage the needle.

Don’t worry if you notice a small air bubble or drop of liquid at the end of the needle - this is normal.

3

Gently hold the skin around the sterilised area using your thumb and index finger.

4

Holding the syringe like a pencil with your other hand, insert the needle at a 45° angle, with one quick motion, into the area of skin you are holding.

5

You should push the plunger down slowly but firmly, until all the fluid has been injected.

Keep the pressure on the plunger as you take the needle out.

6

Gradually take your thumb off the plunger, allowing the empty syringe to move up until the needle guard fully covers the needle.

Don’t worry if there is a small amount of blood or liquid at the injection site afterwards - this is normal. It may help to press on the area with a cotton ball, but do not rub the skin.

Hide text instructions

Disposing of Simponi

You will be given a sharps bin to dispose of all used pens or syringes.

Never throw away SmartJect pens or syringes with household waste.

Delivery & Collection

You can organise the delivery and collection of your sharps bin by telephoning one of the numbers below, and asking to speak to a Patient Services Advisor.

0808 168 0157

0333 103 9817

Mon-Fri: 8am - 8pm

Weekends: 8am - 4:30pm

A few things to note

Simponi has been specially formulated to minimise any pain you might experience during injection, but there are some things you may also do to help reduce injection pain:

Do

  • Allow 30 minutes for Simponi to reach room temperature before injection
  • Wait until all the alcohol has evaporated after cleaning the area before injecting
  • Relax your muscles at the site before and during injection
  • Keep the SmartJect pen/syringe still throughout the injection

Don't

  • Store Simponi in the freezer
  • Try to warm Simponi quickly, such as in the microwave
  • Shake the SmartJect pen or syringe
  • Remove the cap or needle cover while waiting for it reach room temperature
  • Touch, fan or blow on the injection site after cleaning with the alcohol wipe
  • Inject if the liquid appears cloudy or has particles in it
  • Inject if Simponi is past its expiry date or the seal is broken
  • Inject if the SmartJect pen has been dropped without the cap on
  • Reuse the same SmartJect pen or syringe

If you notice anything unusual, contact your healthcare professional, especially if:

  • The injection site continues to bleed
  • The injection is very painful
  • A rash develops around the injection site
  • You get a fever or develop signs of an allergic reaction

Contact

For further information about Simponi (golimumab) please contact our Medical Information Department at:

Medical Information Department

Merck Sharp & Dohme Ltd.

Hertford Road

Hoddesdon

Hertfordshire

EN11 9BU

Tel: 01992 467272

E-mail: medicalinformationuk@merck.com

External link

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References

  1. Kanai T et al. Korean J Intern Med 2014; 29(4): 409-15
  2. Olendzki BC et al. Nutr J 2014; 13(5): 1-7.
  3. Brown AC et al. Expert Rev. Gastroenterol. Hepatol 2011; 5(3): 411-25
  4. Pituch-Zdanowksa A et al. Prz Gastroenterol 2015; 10(3): 135-41.
  5. Oliviero F et al. Swiss Med Wkly 2015; 145: w14190.
  6. Clinton CM et al. Arthritis 2015; 2015: Article ID 708152.
  7. Narula N, Fedorak RN. Can J Gastroenterol 2008; 22 (5): 497-504
  8. Bilski J et al. BioMed Res Int 2014; Volume 2014 (Article ID 429031): 1-14.
  9. Benatti FB, Pedersen BK. Nat Rev Rheumatol 2015; 11: 86-97
  10. Nolte K et al. S Afr Fam Pract 2013; 55: 345-9
  11. Metsios GA et al. Expert Rev Clin Immunol 2015; 11: 1121-30
  12. Brophy S et al. Semin Arthritis Rheum 2013; 42: 619-26

SmartJect Pen

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